Sample annotations and Descriptor schemas

When working with the biological data, it is recommended (and often required) to properly annotate samples and sample data.

Sample metadata / sample annotations are managed through the Resolwe SDK. You can find the tutorial on how to manage sample annotation is the Annotate Samples section of the Resolwe SDK documentation.

The annotation fields associated with the sample data are defined in the descriptor schemas. This tutorial describes the descriptor schemas that are attached to the raw sequencing reads and differential expressions files. Other available descriptor schemas can be explored at the Resolwe-bio GitHub page.

Reads

To annotate raw sequencing reads we have prepared corresponding reads descriptor schema.

Differential expression

To define the default thresholds for p-value, log fold change (FC) and to describe which samples are used as cases and which as controls in the calculation of differential expression we have prepared diffexp descriptor schema.